Is it the hip Mission District - where the best Mexican food north of the border awaits and the gallery and nightlife scene is at its creative best?
Maybe you like The Castro best - where you can be who you wanna be and party till dawn?
Or do you prefer the Haight-Ashbury, where the hippie scene survives and a chilled-out lifestyle prevails?
Or maybe, just maybe, you come to San Francisco mainly to leave the country altogether by slipping into the sights, sounds and smells of the most authentic and pictureque Asian community in the western hemisphere: Chinatown.
Vote for your favorite neighborhood below, and let the world know: